ldlr null mice (Jackson Laboratory)
90
Structured Review
Jackson Laboratory
ldlr null mice
Ldlr Null Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ldlr+null+mice/c57bl+6j+mice/pm35417135-163-13-19
Average 90 stars, based on 1 article reviews
Ldlr Null Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ldlr+null+mice/c57bl+6j+mice/pm35417135-163-13-19
Average 90 stars, based on 1 article reviews
ldlr null mice - by Bioz Stars,
2026-09
90/100 stars
Images
Related Articles
Generated:Article Title: Expression of Chitotriosidase in Macrophages Modulates Atherosclerotic Plaque Formation in Hyperlipidemic Mice. Article Snippet: .. Wild-type C57BL/6 mice and Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo Article Snippet: .. In vivo studies in mice Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJL-Tg[CETP]; Taconic, Hudson, NY) with Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo Article Snippet: .. Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJL-Tg[CETP]; Taconic, Hudson, NY) with Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S] Article Snippet: .. Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJLTg[CETP]; Taconic, Hudson, NY) with In Vivo:Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo Article Snippet: .. In vivo studies in mice Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJL-Tg[CETP]; Taconic, Hudson, NY) with Over Expression:Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo Article Snippet: .. In vivo studies in mice Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJL-Tg[CETP]; Taconic, Hudson, NY) with Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo Article Snippet: .. Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJL-Tg[CETP]; Taconic, Hudson, NY) with Article Title: A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S] Article Snippet: .. Cholesteryl ester transfer protein (CETP)/LDLr-hemi mice, which are hemizygous for overexpression of the human CETP and heterozygous for LDLr, were generated by crossing mice overexpressing ApoAI promoter-driven human CETP (B6;SJLTg[CETP]; Taconic, Hudson, NY) with Clinical Proteomics:Article Title: Cardiometabolic Syndrome: An Update on Available Mouse Models. Article Snippet: .. Furthermore, when Ldlr / mice are placed on a diet with greater than 20% fat content, they also become obese, display insulin resistance (IR), and impaired glucose tolerance.24 Apoe / mice develop a more severe hyperlipidemia, with an increase in plasma cholesterol levels and TG levels, which leads to spontaneous atherosclerosis onanormaldiet.23 Inmanycases, Apoe / mice do not become obese, nor do they develop IR, even on a high-fat diet (HFD).25,26 However, there has been a case where Apoe / mice fed HFD (60% fat) for 17 weeks displayed increased body weight, glucose intolerance, and an increase in systemic inflammation, which indicates that modulation of the feeding protocol can have a significant biological effect.27 In general, as summarized by the Jackson Laboratory and the Mouse Phenome Database which have phenotyped 8-week old male and female Apoe and Article Title: Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists. Article Snippet: Hyperlipidemia and increased circulating cholesterol levels are associated with increased cardiovascular disease risk.. The liver X receptors (LXRs) are regulators of de novo lipogenesis and cholesterol transport and have been validated as potential therapeutic targets for the treatment of atherosclerosis.. However, efforts to develop LXR agonists to reduce cardiovascular diseases have failed due to poor clinical outcomes-associated increased hepatic lipogenesis and elevated low-density lipoprotein (LDL) cholesterol (C). other:Article Title: Dyslipidemia Induces Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense through Divergent TLR Response Phenotypes Article Snippet: C57BL/6 and |